Innovative Device
COLPOFIX® IS AN INNOVATIVE VAGINAL SPRAY GEL
Colpofix® is a vaginal spray gel indicated for the prevention and treatment of cervical lesions caused by the human papillomavirus (HPV).
It has been a success in its country of origin, Italy, and is already present in several other European markets.
Colpofix® is one of our most promising products and was awarded by the Excellence in Pharma: Highly commended 2020 prize in the Finished Formulation category at CPhI Worldwide 2020, the largest and most prestigious pharmaceutical event in the world.
HPV is the most common sexually transmitted infection in the world, and the most virulent genotypes may cause cervical lesions to develop, which are implicated in cervical cancer.
The main components of Colpofix® are polycarbophil and carboxymethyl beta-glucan. It has been evaluated through 4 studies involving more than 2,000 patients, in which it demonstrated both clinical efficacy and a very high safety profile.
COLPOFIX® INNOVATIVE VAGINAL SPRAY GEL
![Colpofix® – What is Colpofix®? – Innovation Colpofix® - What is Colpofix®? - Innovation](https://storage.googleapis.com/statics-pro-colpofix-uriach-web/sites/1/2021/08/SEGELL-innovation.png)
![Colpofix® – Professional Area – Innovative Device – Innovative Vaginal Spray Gel – The Exclusive Ergonomic Cannula Colpofix® - Professional Area - Innovative Device - Innovative Vaginal Spray Gel - The Exclusive Ergonomic Cannula](https://storage.googleapis.com/statics-pro-colpofix-uriach-web/sites/1/2021/09/Colpofix_Ergonomic_Exclusive_Cannula.jpg)
THE EXCLUSIVE ERGONOMIC CANNULA
allows the cervix to be reached
![Colpofix® – Professional Area – Innovative Device – Innovative Vaginal Spray Gel – Maximum Uniform Distribution Gel Colpofix® - Professional Area - Innovative Device - Innovative Vaginal Spray Gel - Maximum Uniform Distribution Gel](https://storage.googleapis.com/statics-pro-colpofix-uriach-web/sites/1/2021/09/Colpofix_Maximum_Uniform_Distribution_Gel.jpg)
MAXIMUM UNIFORM DISTRIBUTION OF GEL
over the cervical-vaginal mucous
Colpofix® is totally compatible with natural rubber latex condoms
Composition and mode of action
COMPLEMENTARY EFFECT OF ITS COMPONENTS
![Colpofix® – What is Colpofix®? – Composition Colpofix® - What is Colpofix®? - Composition](https://storage.googleapis.com/statics-pro-colpofix-uriach-web/sites/1/2021/08/Colpofix-Composition.jpg)
The biofilm formed by polycarbophil allows for the bioadhesion of carboxymethyl beta-glucan to the cervical tissue, ensuring its distribution and increasing the contact time, which in turn allows for the prolonged action of its effects.
A) Carboxymethyl beta-glucan
B) Polycarbophil
CARBOXYMETHYL BETA-GLUCAN
![Colpofix® – Professional Area – Composition and mode of action – Complementary effect of its components – Carboxymethyl Beta-Glucan Prebiotic effect Colpofix® - Professional Area - Composition and mode of action - Complementary effect of its components - Carboxymethyl Beta-Glucan Prebiotic effect](https://storage.googleapis.com/statics-pro-colpofix-uriach-web/sites/1/2021/09/Colpofix_Polycarbophil_Prebiotic_effect.jpg)
Contributes to the maintenance and restoration of the vaginal microbiota through a specific prebiotic effect: providing a specific source of energy for Lactobacillus sp., thereby promoting their growth and domination of the vaginal microenvironment.
POLYCARBOPHIL
![Colpofix® – Professional Area – Composition and mode of action – Complementary effect of its components – Polycarbophil protective film Colpofix® - Professional Area - Composition and mode of action - Complementary effect of its components - Polycarbophil protective film](https://storage.googleapis.com/statics-pro-colpofix-uriach-web/sites/1/2021/09/Colpofix_Polycarbophil_Protective_Film.jpg)
In association with mucin, it forms a mucoadhesive protective film, which remains in situ for a prolonged period.
This protective mucoadhesive film shields the vaginal mucosa from external microbial agents, as well as supporting the maintenance and control of the physiological conditions in the transformation zone of the cervical-vaginal mucosa through moisturisation.
Patient profile
Colpofix® can be used:
FOR THE REGRESSION OF LOW-GRADE CERVICAL LESIONS
AS A RECOVERY TREATMENT AFTER CERVICAL SURGERY ON HIGH-GRADE CERVICAL LESIONS
![Colpofix® – Professional Area – Patient Profile – For the Regression of Low-Grade Cervical Lesions Colpofix® - Professional Area - Patient Profile - For the Regression of Low-Grade Cervical Lesions](https://storage.googleapis.com/statics-pro-colpofix-uriach-web/sites/1/2021/09/Colpofix_Low_Grade_Cervical_Lesions-300x300.png)
![Colpofix® – What is Colpofix®? – Colpofix International Colpofix® – What is Colpofix®? - Colpofix International](https://storage.googleapis.com/statics-pro-colpofix-uriach-web/sites/1/2021/11/pack_Colpofix_ENG.png)
![Colpofix® – Professional Area – Patient Profile – As a Recovery Treatment After Cervical Surgery on High-Grade Cervical Lesions Colpofix® - Professional Area - Patient Profile - As a Recovery Treatment After Cervical Surgery on High-Grade Cervical Lesions](https://storage.googleapis.com/statics-pro-colpofix-uriach-web/sites/1/2021/09/Colpofix_Recovery_Treatment_After_Cervical_Surgery-300x300.png)
Colpofix® can be used:
FOR THE REGRESSION OF LOW-GRADE CERVICAL LESIONS
![Colpofix® – Professional Area – Patient Profile – For the Regression of Low-Grade Cervical Lesions Colpofix® - Professional Area - Patient Profile - For the Regression of Low-Grade Cervical Lesions](https://storage.googleapis.com/statics-pro-colpofix-uriach-web/sites/1/2021/09/Colpofix_Low_Grade_Cervical_Lesions-200x200.png)
![Colpofix® – What is Colpofix®? – Colpofix International Colpofix® – What is Colpofix®? - Colpofix International](https://storage.googleapis.com/statics-pro-colpofix-uriach-web/sites/1/2021/11/pack_Colpofix_ENG.png)
AS A RECOVERY TREATMENT AFTER CERVICAL SURGERY ON HIGH-GRADE CERVICAL LESIONS
![Colpofix® – Professional Area – Patient Profile – As a Recovery Treatment After Cervical Surgery on High-Grade Cervical Lesions Colpofix® - Professional Area - Patient Profile - As a Recovery Treatment After Cervical Surgery on High-Grade Cervical Lesions](https://storage.googleapis.com/statics-pro-colpofix-uriach-web/sites/1/2021/09/Colpofix_Recovery_Treatment_After_Cervical_Surgery-200x200.png)
How to use
HOW TO USE COLPOFIX®?
Posology
![Colpofix® – Professional Area – Posology Colpofix® - Professional Area - Posology](https://storage.googleapis.com/statics-pro-colpofix-uriach-web/sites/1/2021/11/Professional_Area_Colpofix_Posology.jpg)
![Colpofix® – Professional Area Colpofix® - Professional Area](https://storage.googleapis.com/statics-pro-colpofix-uriach-web/sites/1/2021/11/Banner_Profesional_Area_Colpofix.jpg)